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Cytochrome P450 (e.g. CYP17) Cytochrome P450 (e.g. CYP17)

Cat.No.  Name Information
M3326 Memantine hydrochloride Memantine hydrochloride is a CYP2B6 and CYP2D6 inhibitor for recombinant CYP2B6 and CYP2D6 with Ki of 0.51 nM and 94.9 μM, respectively.
M2079 Chrysin Chrysin is a naturally occurring flavone chemically extracted from the passion flowers Passiflora caerulea.
M14315 Pradefovir mesylate Pradefovir mesylate is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 μM.
M14313 Friedelin Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart).
M14312 Curcumenol Curcumenol ((+)-Curcumenol) is a potent CYP3A4 inhibitor with an IC50 of 12.6 μM, which is one of constituents in the plants of medicinally important genus of Curcuma zedoaria, with neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities.




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