About 2 results found for searched term "Zetomipzomib" (0.131 seconds)
Cat.No. | Name | Target |
---|---|---|
M21181 | Zetomipzomib | Proteasome |
KZR-616 | ||
Zetomipzomib (KZR-616) is the first immunoproteasome inhibitor that selectively targets the immunoproteasome subunits LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7). Zetomipzomib has potential for use in a variety of autoimmune diseases. | ||
M21515 | Zetomipzomib maleate | Proteasome |
KZR-616 maleate | ||
Zetomipzomib (KZR-616) maleate is a first-in-class inhibitor of immunoproteasome that selectively targets the immunoproteasome subunit LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50:131/179 nM=hLMP7/mLMP7). Potential of Zetomipzomib maleate for use in multiple autoimmune diseases. |
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