About 6 results found for searched term "Z-L-Val-OH" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M38910 | Z-L-Val-OH | Others |
| Z-L-Val-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M4228 | Neferine | NF-κB |
| (-)-Neferine | ||
| Neferine is a bisbenzylisoquinoline alkaloid extracted from Plumbago officinalis, which reduces lipid accumulation and promotes β-oxidation through activation of the AMPK pathway in hepatocytes, and possesses anti-inflammatory, antioxidant, and antipulmonary fibrosis activities. In addition, Neferine potently inhibits NF-κB activation.The affinity Kd value of Neferine for ABCB1 is 0.659 μM.It can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M11278 | GNA002 | Histone Methyltransferase |
| GNA002 is a potent, selective, covalent EZH2 inhibitor with an IC50 of 1.1 μM against EZH2. GNA002 can specifically and covalently bind Cys668 in the EZH2-SET domain to induce EZH2 degradation through COOH terminal of ubiquitination mediated by Hsp70 interacting protein (CHIP). GNA002 effectively reduced EZH2-mediated H3K27 trimethylation and reactivated tumor suppressor genes silenced by Polycomb repressor complex 2 (PRC2). | ||
| M40875 | Brazikumab | IL Receptor/Related |
| AMG 139; MEDI2070 | ||
| Brazikumab is a human IgG2 monoclonal antibody targeting IL-23 that selectively binds to the p19 subunit of IL-23 and has a KD value of 0.138 nM against human IL-23 for Crohn's disease (CD). | ||
| M40989 | Azemiglitazone potassium | PPAR |
| MSDC-0602K | ||
| Azemiglitazone potassium is a thiazolidinediones that binds to PPARγ with an IC50 value of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (MPC). It can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
| M49467 | Carfloglitazar sodium | PPAR |
| Chiglitazar sodium | ||
| Carfloglitazar sodium is a dual agonist of the pan peroxisome proliferator-activated receptor (PPARα/γ) with EC50 values of 1.2, 0.08, and 1.7 μM for PPARα, PPARγ, and PPARδ, respectively.It can be used in studies related to nonalcoholic steatohepatitis (NASH). | ||
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