About 3 results found for searched term "YAP-TEAD-IN-3" (0.156 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43572 | IAG933 | YAP |
| YAP-TEAD-IN-3 | ||
| IAG933 is a first-in-class, selective and orally efficacious YAP1/WWTR1(TAZ)-panTEAD protein-protein interaction inhibitor. IAG933 specifically abrogates the interaction between YAP/TAZ coactivators and all four TEAD isoforms, thus selectively inhibiting TEAD-driven transcriptional activity and inducing anti-cancer effects. | ||
| M31171 | YAP/TAZ inhibitor-2 | YAP |
| YAP/TAZ inhibitor-2 is a potent, orally bioavailable TEAD-YAP/TAZ inhibitor with an EC50 value of 3 nM that exhibits anticancer and antiproliferative activity. | ||
| M55023 | VT3989 | YAP |
| VT-3989 | ||
| VT3989 is a first-in-class, orally active, potent and selective YAP/TEAD auto-palmitoylation inhibitor. VT3989 works by inhibiting TEAD palmitoylation, which in turn blocks YAP function. | ||
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