About 12 results found for searched term "W-7 hydrochloride" (0.06 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1909 | GW 791343 dihydrochloride | P2 Receptor |
| GW 791343 dihydrochloride is a non-competitive inhibitor of human P2X(7) receptor. | ||
| M3233 | GW791343 trihydrochloride | P2 Receptor |
| GW791343 trihydrochloride is ahydrochloride salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7. | ||
| M5863 | Pazopanib HCl (GW786034) | VEGFR/PDGFR |
| GW786034; Pazopanib Hydrochloride | ||
| Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. | ||
| M6544 | BW 723C86 hydrochloride | Others |
| BW 723C86 hydrochloride is a 5-HT 2B agonist. | ||
| M7481 | W-7 hydrochloride | CaMK |
| W7 hydrochloride | ||
| W-7 Hydrochloride is a selective calmodulin antagonist. W-7 Hydrochloride inhibits Ca2+ -calmodulin-dependent phosphodiesterase and Myosin light chain kinase. The IC50 values were 28 μM and 51 μM, respectively. W-7 Hydrochloride can induce apoptosis and has anti-cancer activity. | ||
| M7484 | WAY 207024 dihydrochloride | Others |
| WAY 207024 dihydrochloride is a gnRH receptor antagonist. | ||
| M14173 | GW806742X hydrochloride | Necroptosis |
| GW806742X hydrochloride is an ATP mimetic and potent inhibitor of MLKL and necroptosis, slowing down MLKL membrane translocation and binding to the MLKL pseudokinase domain with a Kd value of 9.3 μM. GW806742X hydrochloride has anti-VEGFR2 activity (IC50=2 nM). GW806742X hydrochloride has anti-VEGFR2 activity (IC50=2 nM). | ||
| M14944 | Vactosertib Hydrochloride | TGF-β Receptor |
| EW-7197 Hydrochloride; TEW-7197 Hydrochloride | ||
| Vactosertib Hydrochloride (EW-7197 Hydrochloride) is a potent, orally active and ATP-competitive activin receptor-like kinase 5 (ALK5) inhibitor with an IC50 of 12.9 nM. | ||
| M30118 | Aplaviroc hydrochloride | CCR |
| AK602 hydrochloride; GSK-873140 hydrochloride; GW-873140 hydrochloride | ||
| Aplaviroc (AK 602) hydrochloride, a SDP derivative, is a CCR5 antagonist, with IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW. | ||
| M41732 | WAY-181187 hydrochloride | 5-HT Receptor |
| WAY-181187 (SAX-187) hydrochloride is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM. | ||
| M57070 | WYE-687 dihydrochloride | mTOR |
| WYE-687 dihydrochloride is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. | ||
| M56372 | GW274150 dihydrochloride | NO Synthase |
| GW274150 (dihydrochloride) is a potent, selective, orally active and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 μM; Kd=40 nM) and rat iNOS (ED50=1.15 μM). | ||
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