About 10 results found for searched term "VH032" (0.054 seconds)
Cat.No. | Name | Target |
---|---|---|
M9736 | VHL Ligand 1 hydrochloride | Ligand for E3 Ligase |
Protein degrader 1; VH032-NH2 hydrochloride; (S,R,S)-AHPC hydrochloride | ||
VHL Ligand 1 hydrochloride is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. | ||
M9838 | VH032-PEG6-C4-Cl | PROTAC |
(S,R,S)-AHPC-PEG6-C4-Cl; E3 ligase Ligand-Linker Conjugates 9 | ||
(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker. | ||
M14862 | (S,R,S)-AHPC-PEG4-NH2 hydrochloride | PROTAC |
VH032-PEG4-NH2 hydrochloride; VHL Ligand-Linker Conjugates 4 hydrochloride; E3 ligase Ligand-Linker Conjugates 7 | ||
(S,R,S)-AHPC-PEG4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 4-unit PEG linker used in PROTAC technology. | ||
M14864 | (S,R,S)-AHPC | Ligand for E3 Ligase |
VH032-NH2; VHL ligand 1 | ||
(S,R,S)-AHPC (VH032-NH2) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. | ||
M14865 | VH032-cyclopropane-F | Ligand for E3 Ligase |
VHL ligand 3; E3 ligase Ligand 19 | ||
VH032-cyclopropane-F is the VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein (e.g., SMARCA BD ligand) by a linker to form PROTACs (e.g., PROTAC 1). PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4. | ||
M14867 | VH032 | Ligand for E3 Ligase |
VH032 is a VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. VH032 is a VHL/HIF-1α interaction inhibitor with a Kd value of 185 nM. | ||
M28867 | VH032-PEG5-C6-Cl | PROTAC |
HaloPROTAC 2 | ||
VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. | ||
M57105 | VH032-PEG3-acetylene | E3 Ligase Ligand-Linker Conjugates |
VH032-PEG3-acetylene is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. | ||
M55955 | VH032 amide-PEG1-acid | DNA Alkylator/Crosslinker |
VH032 amide-PEG1-acid (linker 10) is a VHL-1 alkyl linker that can be used to bind CDK4/6 ligands (PI) and degradation/destruction tags (EL) (e.g.,E3 ligase ligands). | ||
M57838 | VH 032 amide-PEG4-amine | Others |
VH 032 amide-PEG4-amine |
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