About 1 result found for searched term "UNC-2170 " (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28775 | UNC-2170 | Others |
| UNC-2170 is a functionally active, fragment-like ligand for 53BP1 (IC50=29 µM; Kd=22 µM). UNC-2170 shows at least 17-fold selectivity for 53BP1 as compared to nine other methyl-lysine (Kme) reader proteins. 53BP1 is a Kme binding protein that plays a central role in DNA Damage Repair (DDR) pathways and is recruited to sites of double-strand breaks (DSB). | ||
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