About 4 results found for searched term "Treprostinil" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7428 | Treprostinil | Prostaglandin Receptor |
| UT-15; LRX-15 | ||
| Treprostinil (UT-15) is a potent prostacyclin (PGI 2) analog. | ||
| M20978 | Treprostinil sodium | Prostaglandin Receptor |
| UT-15, Remodulin, Orenitram, Tyvaso, Trevyent | ||
| Treprostinil sodium (UT-15, Remodulin, Orenitram, Tyvaso, Trevyent) is a stabilized tricyclic analog of prostacyclin and a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively. Treprostinil promotes vasodilation and inhibits platelet aggregation in pulmonary and systemic arterial vascular beds, and can be used in studies related to pulmonary arterial hypertension (PAH). | ||
| M28822 | Treprostinil palmitil | Prostaglandin Receptor |
| INS-1009 | ||
| Treprostinil palmitil (TP) is the proagent of DP1 and EP2 agonist, Treprostinil (UT-15), whose EC50 values were 0.6 and 6.2 nM, respectively. Treprostinil palmitil is a pure proagent and possesses no inherent binding to G-protein coupled receptors including prostanoid receptors. | ||
| M30662 | Treprostinil diethanolamine | Prostaglandin Receptor |
| UT-15C | ||
| Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with Ki values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries. | ||
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