About 32 results found for searched term "Thrombin" (0.097 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9804 | Thrombin | Thrombopoietin/Thrombin |
| Thrombin is a trypsin-like allosteric serine protease. | ||
| M9857 | TRP-14 | Peptides |
| TRAP; SFLLRNPNDKYEPF; ThroMbin Receptor Agonist Peptide | ||
| Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe is a synthetic thrombin receptor agonist peptide. | ||
| M52506 | Thrombin receptor peptide ligand | Thrombopoietin/Thrombin |
| Thrombin receptor peptide ligand is a thrombin receptor antagonist peptide that can be used as an antithrombotic agent. | ||
| M52919 | Thrombin Receptor Activator for Peptide 5 (TRAP-5) | PAR |
| Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5) or Proteinase Activated Receptor 1 (1-5), used in the research of coronary heart disease (CHD). | ||
| M1674 | BIBR 953 | Thrombopoietin/Thrombin |
| Dabigatran, Pradaxa; BIBR 953ZW | ||
| BIBR 953 (Dabigatran, Pradaxa) is an oral anticoagulant from the class of the direct thrombin inhibitors. | ||
| M43947 | Enoxaparine | Thrombopoietin/Thrombin |
| Enoxaparine is a low molecular heparin that binds to antithrombin (AT) and accelerates its inhibition of factor Xa.Enoxaparine has a higher affinity for factor Xa than for thrombin, and its action on thrombin does not require HCII (heparin cofactor II). | ||
| M2661 | Edoxaban Tosylate Monohydrate | Factor Xa |
| DU-176b | ||
| Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant compound. | ||
| M3123 | Vorapaxar | PAR |
| SCH 530348 | ||
| Vorapaxar (SCH 530348) is a potent and orally active thrombin receptor (PAR-1) antagonist with Ki of 8.1 nM. | ||
| M3574 | Dabigatran Etexilate | Thrombopoietin/Thrombin |
| BIBR-1048 | ||
| Dabigatran Etexilate is the procompound of dabigatran, a potent, nonpeptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of the thrombin molecule. | ||
| M3717 | Argatroban Monohydrate | Thrombopoietin/Thrombin |
| Argipidine monohydrate | ||
| Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. | ||
| M3759 | Dabigatran etexilate mesylate | Thrombopoietin/Thrombin |
| BIBR 1048MS | ||
| Dabigatran etexilate mesylate is a direct thrombin inhibitor. | ||
| M5008 | Cyclopentyl Chloroformate | Leukotriene Receptor |
| Mandelic acid derivatives and their use as thrombin inhibitors. | ||
| M5219 | AEBSF HCl | Serine/Threonine Protease |
| AEBSF hydrochloride | ||
| AEBSF HCl is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. | ||
| M5465 | Bivalirudin | Others |
| Bivalirudin Trifluoroacetate is a synthetic 20 residue peptide which reversibly inhibits thrombin. | ||
| M6243 | Vorapaxar Sulfate | PAR |
| Vorapaxar is a first-in-class, potent and orally-active protease-activated receptor 1 (PAR-1) antagonist that blocks thrombin-mediated platelet activation without interfering with thrombin-mediated fibrin deposition. | ||
| M8210 | FR-171113 | Others |
| FR171113 was the first non-peptide antagonist of the Protease Activated Receptor-1 (PAR1), also termed thrombin receptor. | ||
| M8658 | Ximelagatran | Thrombopoietin/Thrombin |
| Ximelagatran is orally active, selective and potent direct thrombin inhibitor. | ||
| M9771 | TRAP-6 | Peptides |
| PAR-1 agonist peptide | ||
| TRAP-6 (Thrombin Receptor Activator Peptide 6) is a peptide fragment (residues 42-47) of protease-activated receptor 1 (PAR1) that acts as a PAR1 agonist. | ||
| M10614 | Buddlejasaponin IVb | Others |
| Stellarinpin A; Clinodiside A | ||
| Buddlejasaponin IVb is a triterpene saponin isolated from Clinopodium chinense (Benth.) O. Kuntze, with hemostasis efficacy, shortens thrombin time. | ||
| M13407 | YLF-466D | AMPK |
| C24 | ||
| YLF-466Dis a novel AMPK activator that inhibits thrombin - induced platelet aggregation. | ||
| M13804 | Z-Gly-Gly-Arg-AMC acetate | Fluorescent Dye |
| Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP). | ||
| M14428 | Edoxaban | Factor Xa |
| DU-176 | ||
| Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. | ||
| M14429 | Edoxaban tosylate | Factor Xa |
| DU-176b | ||
| Edoxaban tosylate (DU-176b) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. | ||
| M14537 | Bivalirudin TFA | Thrombopoietin/Thrombin |
| Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin. | ||
| M14538 | Dabigatran (ethyl ester) | Thrombopoietin/Thrombin |
| Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity. | ||
| M14539 | Dabigatran ethyl ester hydrochloride | Thrombopoietin/Thrombin |
| Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor. | ||
| M20396 | Argatroban | Thrombopoietin/Thrombin |
| MCI-9038 | ||
| Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. | ||
| M20440 | Benzamidine HCl | Serine/Threonine Protease |
| Benzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively. | ||
| M21123 | S62798 | Others |
| Thrombin-activatable fibrinolytic inhibitor (TAFIa) inhibitor (S62798) is a fibrinolytic (clot-degrading) agent with an IC50 value of 6 mM. | ||
| M21209 | Heparin Lithium salt | Thrombopoietin/Thrombin |
| Heparin Lithium salt is an anticoagulant that binds reversibly to antithrombin III (ATIII). | ||
| M21312 | BAY 1217224 | Thrombopoietin/Thrombin |
| BAY 1217224 is a neutral non-premedication inhibitor of Thrombin with good oral pharmacokinetics. | ||
| M24629 | Idarucizumab | Others |
| BI 655075 | ||
| Idarucizumab is a humanized monoclonal antibody fragment. Idarucizumab is first reversal agent for a direct oral anticoagulant (DOAC). Idarucizumab can specifically neutralize the effects of the oral direct thrombin inhibitor in order to restore hemostasis. | ||
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