About 2 results found for searched term "Tegaserod" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5992 | Tegaserod maleate | 5-HT Receptor |
| SDZ-HTF-919; HTF-919 | ||
| Tegaserod maleate is a partial agonist of the 5-HT4 receptor; stimulates the peristaltic reflex and accelerates gastrointestinal transit. | ||
| M58580 | Tegaserod | 5-HT Receptor |
| Tegaserod is an orally active serotonin receptor 4 (5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. | ||
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