About 1 result found for searched term "TL4-12 " (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28703 | TL4-12 | MAPKAPK2/MAP3K/MAP4K |
| TL4-12 is a selective MAP4K2/GCK inhibitor, dose-dependently downregulates IKZF1 and BCL-6 and leads to MM cell proliferation inhibition (IC50=37 nM) accompanied by induction of apoptosis. TL4-12 can be used to overcome immunomodulatory agent resistance in multiple myeloma (MM). | ||
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