About 3 results found for searched term "THIP" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7410 | THIP hydrochloride | GABA Receptor |
| Gaboxadol hydrochloride; Lu 02-030 HCl | ||
| THIP hydrochloride (Gaboxadol hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). | ||
| M14221 | THIP | GABA Receptor |
| Gaboxadol | ||
| THIP (Gaboxadol) is a selective δ-aminobutyric acid type A receptor (δ-GABAAR) agonist, functionally selective GABAAR ligand, exhibits agonism at α4β1δ, α4β3δ and weak antagonism at αβγ and α4β2δ GABAARs. | ||
| M40181 | 3-O-trans-p-Coumaroyltormentic acid | Others |
| 3-O-trans-p-Coumaroyltormentic acid is a triterpene having no cytotoxic activity. However, 3-O-cris-p-Coumaroyltormentic acid is a cytotoxic triterpene, can be isolated from the methanol extract of Goreishi (the feces of Trogopterus xanthipes Milne-Edwards). | ||
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