About 6 results found for searched term "TC11" (0.056 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3570 | Candesartan Cilexetil | ATM/ATR |
| TCV-116 | ||
| Candesartan Cilexetil is a specific nonpeptide Ang II receptor (ATR) antagonist and the procompound of candesartan which is an ATR antagonist with an IC50 of 15 μg/kg. | ||
| M3760 | TCS-1102 | OX Receptor |
| TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for OX2 and OX1 receptors respectively). | ||
| M3801 | TCS 21311 | JAK |
| TCS 21311 is a potent JAK3 inhibitor with IC50 of 8 nM. | ||
| M7381 | TCS 1105 | Others |
| TCS 1105 is a gABA A α2 benzodiazepine receptor agonist. | ||
| M30107 | TC-O 9311 | GPR/FFAR |
| TC-O 9311 is a potent orphan G protein-coupled receptor 139 (GPR139) agonist with an EC50 of 39 nM. | ||
| M54520 | TC11 | Caspase |
| TC11 is a phenylphthalimide derivative and an activator of caspase-9 and CDK1, as well as a degrader of MCL1.TC11 is structurally related to immunomodulatory active molecules. During prolonged mitotic blockade, TC11 induces MCL1 degradation and leads to apoptotic death. | ||
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