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TCS 1105

Cat. No. M7381

All AbMole products are for research use only, cannot be used for human consumption.

TCS 1105 Structure
Size Price Availability Quantity
5mg USD 95  USD95 In stock
10mg USD 145  USD145 In stock
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Quality Control & Documentation
Biological Activity

TCS 1105 is a gABAA benzodiazepine receptor (BZR) ligand. Acts as an agonist at α2 and antagonist at α1 benzodiazepine receptors (Ki values are 118 and 245 nM respectively). Anxiolytic agent lacking sedative activity.

Chemical Information
Molecular Weight 296.3
Formula C17H13FN2O2
CAS Number 185391-33-7
Solubility (25°C) DMSO 29.63 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Cosford, et al. J Med Chem. (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors.

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