About 3 results found for searched term "TAS-116" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20676 | Pimitespib | HSP |
| TAS-116 | ||
| TAS-116 is a novel, small-molecule HSP90 inhibitor which inhibits geldanamycin-FITC binding to HSP90 proteins with Ki values of 34.7 nmol/L, 21.3 nmol/L, >50,000 nmol/L, and >50,000 nmol/L for HSP90α, HSP90β, GRP94, and TRAP1, respectively. Furthermore, TAS-116 does not inhibit other ATPases such as HSP70 (IC50 >200 μmol/L). | ||
| M14051 | 1A-116 | Ras |
| 1A-116 is a Rac1 inhibitor, with antitumoral and antimetastatic effects in several types of cancer, such as breast cancer. 1A-116 prevents Rac1-regulated processes involved in the primary tumorigenesis and metastastic processes . | ||
| M43018 | TAS2R14 agonist-1 | Others |
| TAS2R14 agonist is a potent TAS2R14 partial agonist with an EC50 of 116.6 ±23.6 nM. | ||
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