About 1 result found for searched term "TAK-659 " (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28158 | TAK-659 | Syk |
| Mivavotinib | ||
| TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively. TAK-659 induces cell death in tumor cells but not in nontumor cells, and with potential for the treatment of chronic lymphocytic leukemia (CLL). | ||
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