About 6 results found for searched term "Sunitinib" (0.054 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1826 | Sunitinib Malate | VEGFR/PDGFR |
| SU-11248, Sutent | ||
| Sunitinib is a multitargeted tyrosine kinase inhibitor of VEGFR, PDGFRβ and KIT inhibitor with Ki values of 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT, respectively. | ||
| M5066 | N-Desethyl Sunitinib | Metabolite/Endogenous Metabolite |
| SU11662 | ||
| N-desethyl sunitinib is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively). | ||
| M6277 | Sunitinib | VEGFR/PDGFR |
| SU11248 | ||
| Sunitinib is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. | ||
| M14739 | N-Desethyl Sunitinib hydrochloride | VEGFR/PDGFR |
| SU-12662 hydrochloride | ||
| N-Desethyl Sunitinib (SU-12662) (hydrochloride) is a metabolite of sunitinib. | ||
| M49848 | N,N-Didesethyl Sunitinib Hydrochloride | Others |
| N,N-Didesethyl Sunitinib Hydrochloride | ||
| M49849 | Sunitinib Impurity 18 | Others |
| Sunitinib Impurity 18 | ||
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