About 4 results found for searched term "Sophocarpine" (0.135 seconds)
Cat.No. | Name | Target |
---|---|---|
M3913 | Sophocarpine monohydrate | Autophagy |
Sophocarpine monohydrate is a HERG K+ channel blocker with IC50 of 100-300 μM and Na+ channel inward current inhibitor. Sophocarpine monohydrate is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK, and NF-κB signaling pathways. Sophocarpine monohydrate upregulates PTEN expression and inhibits PI3K/Akt phosphorylation, arrests tumor cell cycle and induces apoptosis. Sophocarpine monohydrate inhibits MEK/ERK phosphorylation and VEGF secretion, reducing tumor cell migration. | ||
M3966 | Oxysophocarpine | Others |
OSC | ||
Oxysophocarpine (OSC), a quinolizidine alkaloid extracted from leguminous plants of the genus Robinia, is traditionally used for various diseases including neuronal disorders. | ||
M13570 | Sophocarpine | Autophagy |
Sophocarpine is a PTEN activator and an inhibitor of PI3K/Akt, MEK/ERK, and NF-κB signaling pathways. Sophocarpine upregulates PTEN expression and inhibits PI3K/Akt phosphorylation, arrests tumor cell cycle and induces apoptosis. Sophocarpine inhibits MEK/ERK phosphorylation and VEGF secretion, reducing tumor cell migration. Sophocarpine is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. | ||
M16007 | 9α-Hydroxysophocarpine | Alkaloids |
9α-Hydroxysophocarpine |
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