About 9 results found for searched term "ST247" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1813 | PCI-24781 | HDAC |
| Abexinostat; CRA-024781 | ||
| PCI-24781 is a novel and potent histone deacetylase (HDAC) inhibitor with IC50 value of 0.43 to 2.7 μM. *The compound is unstable in solutions, freshly prepared is recommended | ||
| M8189 | STF-62247 | Autophagy |
| STF62247; STF 62247 | ||
| Stf-62247 is an autophagy inducer with selective cytotoxicity against VHL-deficient renal cell carcinoma, with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively. Stf-62247 can trigger ADCD in glioblastoma cell lines (LN-229, MZ-54, GOS-3 and U343) by inducing dephosphorylation and inactivation of mTORC1. | ||
| M8337 | ST247 | Others |
| ST247 is a PPAR β/δ selective inverse agonist. | ||
| M3486 | NPS-2143 | Calcium-sensing Receptor |
| SB262470 | ||
| NPS-2143 is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor. | ||
| M10851 | LY2922470 | Others |
| LY2922470 is an effective, selective, orally potent GPR40 agonist that acts on human GPR40, mouse GPR40, and rat GPR40 EC50 The values are 7 nM, 1 nM, and 3 nM, respectively. LY2922470 lowers blood glucose levels while significantly increasing insulin and GLP-1, potentially for use in the study of type 2 diabetes mellitus (T2DM). | ||
| M15056 | Recombinant Human/Murine/Rat BDNF (E.coli) | Cytokines and Growth Factors |
| Brain-Derived Neurotrophic Factor; BDNF; Abrineurin | ||
| Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed. Accession #: P23560. | ||
| M21193 | SAR247799 | S1P Receptor |
| S1P1 agonist 3 | ||
| The S1P1 agonist SAR247799 is a biased agonist of the S1P1 sphingosine receptor, preferentially activating G protein signaling over the β-arrestin and internalization pathways. | ||
| M22454 | Recombinant Human STC-1 (HEK293, C-6His) | Cytokines and Growth Factors |
| Stanniocalcin 1 | ||
| Recombinant Human Stanniocalcin 1/STC-1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala247 is expressed with a 6His tag at the C-terminus. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. | ||
| M28474 | HDAC3-IN-T247 | HDAC |
| HDAC3-IN-T247 is a potent and selective HDAC3 (histone deacetylase 3) inhibitor, with an IC50 of 0.24 µM. HDAC3-IN-T247 induces a selective increase of NF-κB acetylation in HCT116 cells. HDAC3-IN-T247 shows anticancer and antiviral activity. HDAC3-IN-T247 inhibits growth of cancer cells, and activates HIV gene expression in latent HIV-infected cells. | ||
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