About 2 results found for searched term "SRT 1720" (0.172 seconds)
Cat.No. | Name | Target |
---|---|---|
M1824 | SRT1720 Hydrochloride | Sirtuin |
SRT-1720 Hydrochloride | ||
SRT1720 Hydrochloride is a selective small molecule activator of SIRT1 that is 1,000-fold more potent than resveratrol (EC1.5 = 0.16 versus 46.2 µM, respectively). SRT1720 increased the activity of SIRT1 and AMPKα phosphorylation at Ser485 via the cAMP-protein kinase A (PKA) pathway. | ||
M11030 | SRT 1720 | Sirtuin |
SRT 1720 is a potent activator of the human SIRT1, EC1.5 The value is 0.16 μM and simultaneously inhibits SIRT2 and SIRT3, EC1.5 The values are 37 μM and > 300 μM, respectively. |
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