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 About 17 results found for searched term "SL-4" (0.051 seconds)

Cat.No.  Name Target
M2053 Wortmannin (KY 12420) PI3K
SL-2052; KY-12420
Wortmannin (KY 12420) is a specific, covalent inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) with IC50 of 3 nM.
M5395 Alfuzosin Androgen Receptor
SL 77499
Alfuzosin is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH).
M5396 Alfuzosin HCl Androgen Receptor
SL 77499-10
Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH).
M5792 Mizolastine Histamine Receptor
SL 850324
Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
M9474 SLV-2436 MNK
SEL-201
SLV-2436 (SEL201-88) is a novel ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 nM and 5.4 nM, respectively.
M24892 Tagraxofusp IL Receptor/Related
SL-401
Tagraxofusp (SL-401) is a potent IL-3 receptor inhibitor to inhibits plasmacytoid dendritic cells (pDCs) growth in multiple myeloma (MM) bone marrow (BM) microenvironment. Tagraxofusp has synergistic effect with Bortezomib and Pomalidomide to suppress multiple myeloma (MM).
M25133 Anumigilimab CSF-1R (c-Fms)
CSL-324
Anumigilimab (CSL-324) is an humanized IgG2a mAb against human granulocyte colony-stimulating factor (G-CSF) receptor. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation.
M27844 Varlitinib tosylate EGFR/HER2
ASLAN001 tosylate; ARRY-334543 tosylate
Varlitinib (ASLAN001) tosylate is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively.
M29002 SLM6031434 hydrochloride  SPHK
SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research.
M30122 Ibipinabant Cannabinoid
SLV319; BMS-646256
Ibipinabant (SLV319) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor, with a Ki of 7.8 nM. Ibipinabant shows more than 1000-fold selectivity for CB1 over CB2 (Ki=7943 nM). Ibipinabant can be used for the research of obesity and diabetic.
M30878 SLX-4090  Others
SLX-4090 is an orally active enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia.
M40645 SL-172154 Others
SL-172154 is a novel fusion protein consisting of human SIRPα and CD40L (SIRPα-Fc-CD40L) linked by human Fc, which can block the CD47 immune checkpoint and activate the CD40 pathway through the dual mechanism of checkpoint blockade and TNF activation.
M41473 qsl-304 DNA/RNA Synthesis
qsl-304 is a DNA gyrase B inhibitor.
M50220 SL-4 Others
SL-4 is a WRN inhibitor that can be used in studies related to gastrointestinal tumors.
M53653 Targeting the bacterial sliding clamp peptide 46 Antibiotic
Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis.
M55361 Recombinant Mouse REG4 Protein (HEK293, His Tag) Cytokines and Growth Factors
Regenerating islet-derived protein 4; GISP; RELP
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium.
M55362 Recombinant Human REG4 Protein (HEK293, C-6His) Cytokines and Growth Factors
Regenerating islet-derived protein 4; GISP; RELP
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium.



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