About 17 results found for searched term "SL-4" (0.051 seconds)
Cat.No. | Name | Target |
---|---|---|
M2053 | Wortmannin (KY 12420) | PI3K |
SL-2052; KY-12420 | ||
Wortmannin (KY 12420) is a specific, covalent inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) with IC50 of 3 nM. | ||
M5395 | Alfuzosin | Androgen Receptor |
SL 77499 | ||
Alfuzosin is an α1 adrenergic receptor antagonist used to treat benign prostatic hyperplasia (BPH). | ||
M5396 | Alfuzosin HCl | Androgen Receptor |
SL 77499-10 | ||
Alfuzosin HCl is an alpha1 receptor antagonist used to treat benign prostatic hyperplasia (BPH). | ||
M5792 | Mizolastine | Histamine Receptor |
SL 850324 | ||
Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions. | ||
M9474 | SLV-2436 | MNK |
SEL-201 | ||
SLV-2436 (SEL201-88) is a novel ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 nM and 5.4 nM, respectively. | ||
M24892 | Tagraxofusp | IL Receptor/Related |
SL-401 | ||
Tagraxofusp (SL-401) is a potent IL-3 receptor inhibitor to inhibits plasmacytoid dendritic cells (pDCs) growth in multiple myeloma (MM) bone marrow (BM) microenvironment. Tagraxofusp has synergistic effect with Bortezomib and Pomalidomide to suppress multiple myeloma (MM). | ||
M25133 | Anumigilimab | CSF-1R (c-Fms) |
CSL-324 | ||
Anumigilimab (CSL-324) is an humanized IgG2a mAb against human granulocyte colony-stimulating factor (G-CSF) receptor. Anumigilimab can be used for increasing numbers of neutrophils at sites of inflammation. | ||
M27844 | Varlitinib tosylate | EGFR/HER2 |
ASLAN001 tosylate; ARRY-334543 tosylate | ||
Varlitinib (ASLAN001) tosylate is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively. | ||
M29002 | SLM6031434 hydrochloride | SPHK |
SLM6031434 hydrochloride is a highly selective sphingosine kinase 2 (SphK2) inhibitor with Kis of 0.4 μM, 0.5 μM, >20 μM, 22 μM for mSphK2, rSphK2, mSphK1 and rSphK1, respectively. SLM6031434 hydrochloride decrease Sphingosine 1-phosphate (S1P) levels in U937 monocytic leukemia cells. SLM6031434 hydrochloride has the potential for renal fibrosis research. | ||
M30122 | Ibipinabant | Cannabinoid |
SLV319; BMS-646256 | ||
Ibipinabant (SLV319) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor, with a Ki of 7.8 nM. Ibipinabant shows more than 1000-fold selectivity for CB1 over CB2 (Ki=7943 nM). Ibipinabant can be used for the research of obesity and diabetic. | ||
M30878 | SLX-4090 | Others |
SLX-4090 is an orally active enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia. | ||
M40645 | SL-172154 | Others |
SL-172154 is a novel fusion protein consisting of human SIRPα and CD40L (SIRPα-Fc-CD40L) linked by human Fc, which can block the CD47 immune checkpoint and activate the CD40 pathway through the dual mechanism of checkpoint blockade and TNF activation. | ||
M41473 | qsl-304 | DNA/RNA Synthesis |
qsl-304 is a DNA gyrase B inhibitor. | ||
M50220 | SL-4 | Others |
SL-4 is a WRN inhibitor that can be used in studies related to gastrointestinal tumors. | ||
M53653 | Targeting the bacterial sliding clamp peptide 46 | Antibiotic |
Targeting the bacterial sliding clamp peptide 46 is a short peptide targeting the bacterial sliding clamp(SC), inhibiting SC-dependent DNA synthesis. | ||
M55361 | Recombinant Mouse REG4 Protein (HEK293, His Tag) | Cytokines and Growth Factors |
Regenerating islet-derived protein 4; GISP; RELP | ||
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium. | ||
M55362 | Recombinant Human REG4 Protein (HEK293, C-6His) | Cytokines and Growth Factors |
Regenerating islet-derived protein 4; GISP; RELP | ||
Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium. |
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