About 1 result found for searched term "SKF-83566 hydrobromide " (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M27764 | SKF-83566 hydrobromide | Dopamine Receptor |
| SKF-83566 hydrobromide is a potent, blood-brain permeable and orally active D1-like dopamine receptor (D1DR) antagonist and a weaker competitive antagonist at the vascular 5-HT2 receptor (Ki=11 nM). SKF-83566 is a competitive DAT (dopamine transporter) inhibitor with an IC50 of 5.7 μM. SKF-83566 also shows selective inhibition for adenylyl cyclase 2 (AC2) over AC1 and AC5 in the isolated rabbit thoracic aorta. SKF-83566 can be used for the research of parkinson’s disease and nicotine craving alleviation. | ||
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