About 6 results found for searched term "Retro-2" (0.194 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8438 | Retro-2 | Anti-infection |
| Retro-2 is a non-toxic inhibitor of the endosome-to-Golgi retrograde transport that selectively protect cells from ricin, cholera toxin, and Shiga-like toxins, without affecting compartment morphology, endogenous retrograde cargos, or other trafficking steps. | ||
| M50746 | Retrocyclin-2 | Others |
| Retrocyclin-2 is an antimicrobial peptide against human immunodeficiency virus, influenza A and herpes simplex virus. | ||
| M28768 | BDM-2 | HIV Protease |
| BDM-2 is an IN-LEDGF allosteric inhibitor (INLAI) of HIV-1 integrase (IN refers to integrase) (IC50=47 nM) with potent anti-Retroviral (ARV) activity. BDM-2 shows IN multimerization activation effect with an AC50 value of 20 nM. BDM-2 blocks the interaction between the catalytic core domain of IN (IN-CCD) and the Integrase binding domain of LEDGF/p75 (IBD), with an IC50 value of 0.15 μM. BDM-2 exhibits highly selective and favorable cytotoxicity. | ||
| M30871 | Tenofovir exalidex | HIV Protease |
| CMX-157 | ||
| Tenofovir exalidex (CMX157) is a lipid conjugate of the acyclic nucleotide analog Tenofovir with activity against both wild-type and antiretroviral drug-resistant HIV strains, including multidrug nucleoside/nucleotide analog-resistant viruses. Tenofovir exalidex is active against all major subtypes of HIV-1 and HIV-2 in fresh human PBMCs and against all HIV-1 strains evaluated in monocyte-derived macrophages, with EC50s ranging between 0.2 and 7.2 nM. CMX157 is orally available and has no apparent toxicity. Tenofovir exalidex also shows antiviral activity against HBV. | ||
| M31242 | Transketolase-IN-2 | Transketolase |
| Transketolase-IN-2 is a potent Transketolase inhibitor. Transketolase-IN-2 shows strong inhibition of Digitaria sanguinalis and Amaranthus retroflexus (over 90% at 200 mg/L and about 80% at 100 mg/L). | ||
| M42935 | DNA polymerase-IN-4 | Others |
| DNA polymerase-IN-4, a coumarin derivative, has antiretroviral activity with IC50 value of 134.22 μM. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
