About 8 results found for searched term "RX-37" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M14554 | Leucomethylene blue mesylate | Amyloid |
| TRx0237 mesylate; Methylene blue leuco base mesylate | ||
| Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. | ||
| M41669 | RX-37 | Epigenetic Reader Domain |
| RX-37 is a selective BET inhibitor. | ||
| M10604 | Pirtobrutinib (LOXO-305) | BTK |
| LY 3527727; RXC-005 | ||
| Pirtobrutinib (LOXO-305; LY 3527727; RXC-005) is a first-in-class, highly selective, non-covalent, next-generation BTK inhibitor with an IC50 of 5.69 nM in WT BTK HEK cells.Pirtobrutinib's selectivity for BTK more than 300 times more selective than other 370 kinases. Pirtobrutinib can be used in studies related to chronic lymphocytic leukemia (CLL). | ||
| M8199 | SR11237 | RAR/RXR |
| SR11237 is a retinoid X receptor (RXR) selective agonist without any RAR activity that leads to the formation of RXR/RXR homodimers and activation of reporter genes containing RXR response elements. In addition, SR11237 significantly promotes reprogramming. | ||
| M10328 | MRX-2843 | FLT3 |
| UNC2371 | ||
| MRX-2843 (UNC2371) is a potent and orally active inhibitor of MERTK and FLT3 with IC50 values of 1.3 nM and 0.64 nM, respectively. | ||
| M14787 | TRFS-green | Others |
| TRFS-green is a highly selective off−on fluorescent probe for imaging thioredoxin reductase (TrxR) in living cells. TRFS-green has the maximum absorbance at around 373 nm. | ||
| M21154 | NRX-252114 | Others |
| NRX-25211 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, enhancing the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-25211 was able to promote the degradation of mutant β catenin degradation. | ||
| M29815 | NRX-103094 | PROTAC |
| NRX-103094 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin peptide for β-TrCP with an EC50 of 62 nM and a Kd of 0.6 nM. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
