About 10 results found for searched term "ROCK2-IN-5" (0.152 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M49538 | ROCK2-IN-5 | ROCK |
| ROCK2-IN-5 is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. | ||
| M11024 | ROCK2-IN-2 | ROCK |
| Rock2-in-2 is a selective ROCK2 inhibitor with IC50 <1 μM. | ||
| M13726 | Chroman 1 | ROCK |
| Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM. | ||
| M13729 | LX7101 | ROCK |
| LX7101 is a potent inhibitor of LIMK and ROCK2 with IC50 values of 24, 1.6 and 10 nM for LIMK1, LIMK2 and ROCK2, respectively; also inhibits PKA with an IC50 less than 1 nM. | ||
| M13731 | ROCK inhibitor-2 | ROCK |
| ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC50s of 17 nM and 2 nM, respectively. | ||
| M30754 | PT-262 | ROCK |
| PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 μM. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent pathway. PT-262 blocks cytoskeleton function and cell migration. PT-262 has anti-cancer activity. | ||
| M41592 | THK01 | ROCK |
| THK01 is a potent ROCK2 inhibitor with IC50 values of 5.7 and 923 nM for ROCK2 and ROCK1, respectively. | ||
| M49541 | ROCK-IN-32 | ROCK |
| ROCK-IN-32 is a ROCK inhibitor, with an IC50 value of 11 nM for ROCK2. | ||
| M49543 | ROCK-IN-6 | ROCK |
| ROCK-IN-6 is a potent and selectiveROCK2 inhibitor with an IC50 of 2.19 nM. | ||
| M49772 | Akt/ROCK-IN-1 | ROCK |
| Akt/ROCK-IN-1 (B12) is a dual inhibitor for Akt and ROCK, with the IC50s of 0.023 nM and 1.47 nM, respectively. | ||
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