About 3 results found for searched term "RO9021" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1989 | CHIR-99021 HCl | GSK-3 |
| Laduviglusib hydrochloride; CHIR-99021 hydrochloride | ||
| CHIR-99021 HCl (Laduviglusib; CT99021) is a hydrochloride of CHIR-99021, with IC50 of 10 nM and 6.7 nM for GSK-3α and GSK-3β, respectively. | ||
| M6594 | CHIR 99021 trihydrochloride | GSK-3 |
| Laduviglusib trihydrochloride; CT99021 trihydrochloride | ||
| Laduviglusib (CHIR-99021) trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. | ||
| M20593 | RO9021 | Syk |
| RO9021 potently inhibits SYK kinase activity with an average IC50 of 5.6 nM and suppresses B-cell receptor signaling. | ||
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