About 8 results found for searched term "RIPK2-IN-3" (0.131 seconds)
Cat.No. | Name | Target |
---|---|---|
M41369 | RIPK2-IN-3 | RIPK |
RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor. | ||
M5209 | GSK481 | RIPK |
GSK481 is a highly effective, selective and specific RIPK1 inhibitor with an IC50 value of 1.3 nM, which can inhibit the phosphorylation of Ser166 in wild-type human RIPK1 (IC50 value of 2.8 nM). The IC50 value of GSK481 against U937 cells was 10 nM. | ||
M8951 | WEHI-345 | RIPK |
WEHI345 | ||
WEHI-345 is a potent and selective RIPK2 inhibitor with IC50 of 0.13 μM. WEHI-345 delays RIPK2 ubiquitylation and NF-κB activation on oligomerization domain (NOD) stimulation. | ||
M28745 | OD36 | RIPK |
OD36 is a RIPK2 inhibitor with an IC50 of 5.3 nM. OD36 is a macrocyclic inhibitor with potent binding to the ALK2 kinase ATP pocket. OD36 shows ALK2-directed activity with KDs of 37 nM. | ||
M29295 | RIPK-IN-4 | RIPK |
RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM. | ||
M29760 | RIPK3-IN-2 | RIPK |
RIPK3-IN-2 is a RIP3 inhibitor. RIPK3-IN-2 can be used in diseases caused by or associate with activated necrotic pathways research. | ||
M41365 | RIPK2/3-IN-1 | RIPK |
RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. | ||
M55904 | OD36 hydrochloride | RIPK |
OD36hydrochloride is a RIPK2 inhibitor with an IC50 of 5.3 nM. |
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