About 1 result found for searched term "Propargyl-PEG1-acid" (0.081 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M58639 | Propargyl-PEG1-acid | PROTAC Linker |
| 3-(2-Propynyloxy)propanoic acid | ||
| Propargyl-PEG1-acid is a PEG-based PROTAC linker can be used in the synthesis of BTK-CRBN PROTACs. BTK-CRBN PROTACs act as stoichiometric degraders, resulting in degradation of BTK protein. Degradation of BTK is a result of cereblon E3 ligases family recruitment. Propargyl-PEG1-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | ||
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