About 2 results found for searched term "Pentylenetetrazol" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5870 | Pentylenetetrazol | GABA Receptor |
| Pentylenetetrazole, Metrazole, pentetrazol | ||
| Pentylenetetrazol displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist. | ||
| M29120 | JNJ-61432059 | GluR |
| JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. Exhibits time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, resulting in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models. | ||
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