About 2 results found for searched term "Patritumab" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M24595 | Patritumab | EGFR/HER2 |
| Human Anti-ERBB3 Recombinant Antibody | ||
| Patritumab (Human Anti-ERBB3 Recombinant Antibody) is a neutralizing monoclonal antibody to ERBB3. Patritumab shows a synergy with Cetuximab , potently inhibits the phosphorylation of EGFR, HER2, HER3, ERK, and AKT. Patritumab also induces cell apoptosis and suppresses the growth of pancreatic, non-small cell lung cancer, and colorectal cancer xenograft tumors. | ||
| M25010 | Patritumab deruxtecan | Drug-Linker Conjugates for ADC |
| HER3-DXd; U3-1287; U3-1402 | ||
| Patritumab deruxtecan (HER3-DXd) is an antibody-drug conjugate (ADC) consisting of a fully human anti-HER3 IgG1 monoclonal antibody Patritumab attached to a topoisomerase I inhibitor payload via a tetrapeptide-based cleavable linker. Patritumab deruxtecan shows anticancer activity. | ||
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