About 4 results found for searched term "PI3Kγ inhibitor 7" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M43388 | PI3Kγ inhibitor 7 | PI3K |
| PI3Kγ inhibitor 7 is a potent and orally active PI3Kγ inhibitor with IC50 values of 4768, 878.1, 3.42, 355.2 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, respectively. | ||
| M2609 | CZC24832 | PI3K |
| CZC24832 is the first selective PI3Kγ inhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ. | ||
| M30394 | AS-041164 | PI3K |
| AS-041164 is a potent, selective and orally active PI3Kγ isoform inhibitor with an IC50 of 70 nM. AS-041164 shows less activity against PI3Kα, PI3Kβ, and PI3Kδ (IC50s of 240 nM, 1.45 μM, and 1.70 μM, respectively). AS-041164 has anti-inflammatory effects. | ||
| M43390 | IHMT-PI3K-455 | PI3K |
| IHMT-PI3K-455 is a potent, selective, orally active PI3Kγ/δ dual inhibitor with IC50s of 7.1 nM and 0.57 nM for PI3Kγ and PI3Kδ, respectively. | ||
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