About 4 results found for searched term "PH-002" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8351 | PH-002 | Others |
| PH-002 is an inhibitor of apolipoprotein (apo) E4 intramolecular domain interaction in neuronal cells that restores mitochondrial cytochrome c oxidase subunit 1 levels, rescues impairments of mitochondrial motility and neurite outgrowth. | ||
| M8910 | Pamapimod | p38 MAPK |
| R-1503, Ro4402257 | ||
| Pamapimod is a novel p38 mitogen-activated protein kinase inhibitor, inhibited p38alpha and p38beta enzymatic activity, with IC50 values of 0.014 +/- 0.002 and 0.48 +/- 0.04 microM, respectively. | ||
| M28298 | NCGC00249987 | Phosphatase |
| NCGC00249987 is a highly selective and allosteric Tyr phosphatase activity of Eya2 inhibitor with IC50s of 3 μM and 6.9 μM for Eya2 ED and MBP-Eya2 FL. NCGC00249987 specifically targets migration, invadopodia formation, and invasion of lung cancer cells. | ||
| M30770 | TTT 3002 | FLT3 |
| TTT 3002 is a potent and orally active FLT3 inhibitor. TTT 3002 potently inhibits FLT3 phosphorylation by activating mutations at residue D835, with an IC50 of 0.2 nM. TTT 3002 can be used for AML (acute myeloid leukemia) research. | ||
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