About 6 results found for searched term "PFI-1" (0.231 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2932 | PFI-1 | Epigenetic Reader Domain |
| PFI-1 is a selective BET (bromodomain-containing protein) inhibitor for BRD4 with IC50 of 0.22 μM. | ||
| M5064 | PFI-4 | Epigenetic Reader Domain |
| PFI-4 is a potent and selective BRPF1 bromodomain inhibitor with IC50 of 80 nM. PFI-4 (1.25 µM; 7 or 11 days) inhibits differentiation of human osteoclasts. | ||
| M5128 | PFI-2 | Histone Methyltransferase |
| (R)-PFI-2 | ||
| PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with Ki (app) and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets. | ||
| M9144 | PFI-3 | Epigenetic Reader Domain |
| PFI-3 is a selective chemical probe for SMARCA bromodomains, including SMARCA2, SMARCA4 and PB1(5) bromodomains with a Kd of 89 nM. | ||
| M56872 | PFI-6 | Others |
| PFI-6 is a non-cytotoxic and selective MLLT1/3 probe targeting the YEATS domain of MLLT1 (ENL/YEATS1) and MLLT3 (AF9/YEATS3). | ||
| M56055 | PFI-90 | Histone demethylase |
| PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. | ||
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