About 1 result found for searched term "PF-3644022 " (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28107 | PF-3644022 | MAPKAPK2/MAP3K/MAP4K |
| PF-3644022 is a potent, selective, orally active and ATP-competitive MAPKAPK2 (MK2) inhibitor with an IC50 of 5.2 nM and a Ki of 3 nM. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) with IC50s of 53 nM and 5.0 nM, respectively. PF-3644022 potently inhibits TNFα production and has anti-inflammatory effect. | ||
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