About 3 results found for searched term "Ophiopogonin D" (0.455 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4131 | Ophiopogonin D | PPAR |
| 65604-80-0; 945619-74-9 | ||
| Ophiopogonin D, isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D is a CYP2J3 inducer. By increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs), Ophiopogonin D significantly inhibited Ang Ii-induced NF-κB nuclear translocation and IκBα down-regulation. Intracellular Ca2+ overload and activation of pro-inflammatory cytokines. | ||
| M8488 | Ophiopogonin D' | Sirtuin |
| Ophiopogonin D', isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D' has cytotoxic activity against two human tumor cell lines mG-63 and SNU387. Ophiopogonin D' can induce necrotic apoptosis of prostate cancer LNCaP cells by activating RIPK1. IC50 were 3.09 μM and 3.63 μM, respectively. SIRT1 is activated in a dose-dependent manner by Ophiopogonin D'. | ||
| M18851 | Ophiopogonin D | Others |
| Ophiopogonin D | ||
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