About 5 results found for searched term "Nutlin-3" (0.129 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2185 | Nutlin-3 | Mdm2 |
| Nutlin-3 is a selective MDM2 (mouse double minute 2) antagonist with IC50 of 90 nM. | ||
| M2894 | Nutlin-3a | Mdm2 |
| (-)-Nutlin-3; Rebemadlin | ||
| Nutlin-3a, the active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits the p53/MDM2 interaction with IC50 of 90 nM. | ||
| M2895 | Nutlin-3b | Mdm2 |
| (+)-Nutlin-3 | ||
| Nutlin-3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite enantiomer Nutlin-3a. | ||
| M5700 | Idasanutlin (RG-7388) | Mdm2 |
| RG-7388 | ||
| Idasanutlin (RG-7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM showing improved in vitro binding as well as cellular potency/selectivity. | ||
| M57114 | Nutlin carboxylic acid | Ligand for E3 Ligase |
| Nutlin carboxylic acid (MDM2 ligand 1) is the Nutlin 3-based MDM2 ligand. | ||
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