About 32 results found for searched term "Norepinephrine" (0.624 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9264 | Norepinephrine | Adrenergic Receptor |
| Levarterenol; Levophed; Arterenol | ||
| Norepinephrine is generally considered to be a β1-selective adrenergic receptor agonist with EC50 of 5.37 μM. | ||
| M13896 | Norepinephrine hydrochloride | Adrenergic Receptor |
| Levarterenol hydrochloride; L-Noradrenaline hydrochloride | ||
| Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors. | ||
| M40635 | DL-Norepinephrine hydrochloride | Adrenergic Receptor |
| DL-Norepinephrine hydrochloride is a synthetic phenylephrine that mimics the sympathomimetic effects of endogenous norepinephrine and is also a neurotransmitter targeting the adrenergic receptors α1 and β1, which have been shown to lower the subendocardial partial pressure of oxygen. | ||
| M55423 | DL-Norepinephrine-d6 | Others |
| DL-Norepinephrine-d6 | ||
| M2155 | (1S-cis)-Milnacipran Hydrochloride | 5-HT Receptor |
| Levomilnacipran hydrochloride; F-2695 hydrochloride | ||
| (1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia. | ||
| M2388 | Amitriptyline hydrochloride | 5-HT Receptor |
| Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively. | ||
| M2408 | Atomoxetine hydrochloride | 5-HT Receptor |
| Tomoxetine hydrochloride; LY 139603; (R)-Tomoxetine hydrochloride | ||
| Atomoxetine is a selective norepinephrine (NE) transporter inhibitor with Ki of 5 nM, with 15- and 290-fold lower affinity for human 5-HT and DA transporters. | ||
| M2623 | Desvenlafaxine | 5-HT Receptor |
| O-Desmethylvenlafaxine | ||
| Desvenlafaxine is a serotonin (5-HT) and norepinephrine (NE) reuptake inhibitor with Ki of 40.2 nM and 558.4 nM, respectively. | ||
| M2624 | Desvenlafaxine Succinate | 5-HT Receptor |
| O-Desmethylvenlafaxine succinate hydrate | ||
| Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively. | ||
| M2657 | Droxidopa | Adrenergic Receptor |
| L-DOPS | ||
| Droxidopa is a psychoactive compound and acts as a procompound to the neurotransmitters norepinephrine (noradrenaline) and epinephrine (adrenaline). | ||
| M2739 | Guanethidine Sulfate | Monoamine Oxidase |
| Guanethidine is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine. | ||
| M2852 | Milnacipran hydrochloride | 5-HT Receptor |
| Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively. | ||
| M2796 | Trimipramine Maleate | 5-HT Receptor |
| Trimipramine Maleate is a serotonin transport blocker that also blocks norepinephrine uptake. | ||
| M3246 | Amfebutamone hydrochloride | Dopamine Receptor |
| Bupropion hydrochloride | ||
| Amfebutamone hydrochloride is a selective norepinephrine-dopamine reuptake inhibitor with IC50 of 6.5 and 3.4μM for the reuptake of dopamine and norepinephrine, respectively | ||
| M1588 | Duloxetine Phenolic Impurity | Metabolite/Endogenous Metabolite |
| Para-Naphthol duloxetine | ||
| Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI). | ||
| M1559 | Clomipramine Hydrochloride | 5-HT Receptor |
| Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively. | ||
| M5424 | Asenapine maleate | 5-HT Receptor |
| Org 5222 | ||
| Asenapine maleate is a high-affinity antagonist of various receptors including serotonin receptors (5-HT), norepinephrine (NA), dopamine receptors, and histamine receptors, and can be used in studies related to neurodivergent disorders as well as depressive manic depression. | ||
| M5601 | Duloxetine HCl | 5-HT Receptor |
| (S)-Duloxetine hydrochloride; LY-248686 hydrochloride | ||
| Duloxetine hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD). | ||
| M6050 | Venlafaxine HCl | 5-HT Receptor |
| Wy 45030 hydrochloride | ||
| Venlafaxine HCl is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia. | ||
| M6051 | Venlafaxine | 5-HT Receptor |
| Wy 45030 | ||
| Venlafaxine is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. | ||
| M6664 | Desipramine hydrochloride | Dopamine Receptor |
| Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively. | ||
| M7767 | DOV 216,303 | 5-HT Receptor |
| DOV 216,303 is a potent triple inhibitor of 5-hydroxytryptamine (5-HT), norepinephrine, and dopamine reuptake with IC50 values of 20, 14, and 78 nM, respectively. | ||
| M7847 | Indatraline hydrochloride | Others |
| Potent inhibitor of dopamine, norepinephrine and serotonin uptake. | ||
| M7949 | Nisoxetine hydrochloride | Others |
| Nisoxetine hydrochloride is a potent, selective norepinephrine transporter inhibitor (Ki = 5.1 nM). | ||
| M8026 | Protriptyline hydrochloride | 5-HT Receptor |
| Norepinephrine uptake blocker. | ||
| M25597 | LY03005 hydrochloride | 5-HT Receptor |
| Ansofaxine hydrochloride | ||
| LY03005 hydrochloride, the hydrochloride form of LY03005, is also a triple reuptake inhibitor that inhibits the reuptake of serotonin, dopamine, and norepinephrine with IC50 values of 723 nM, 491 nM, and 763 nM, respectively. | ||
| M10054 | Paroxetine | 5-HT Receptor |
| BRL29060 | ||
| Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs). Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. | ||
| M11396 | Terlipressin diacetate | Vasopressin Receptor |
| Terlipressin diacetate is a vasopressin analogue and a highly selective vasopressin V1 receptor agonist that reduces visceral blood flow and portal vein pressure and controls acute varicose rupture bleeding. Terlipressin diacetate has anti-inflammatory and antioxidant effects and can be used to study hepatorenal syndrome and norepinephrine-resistant septic shock. | ||
| M11426 | AM404 | Cannabinoid |
| N-(4-HYDROXYPHENYL)-ARACHIDONYLAMIDE | ||
| AM404 is an endocannabinoid reuptake inhibitor that can block anandamide transport with IC50 values in the low mole range. The isolated rat hepatic artery was constricted by norepinephrine and relaxed by AM404. PEC50 value was 7.4 (corresponding EC50 value was 0.04 µM). It has neuroprotective effects. | ||
| M13949 | Nomifensine | Dopamine Receptor |
| (±)-Nomifensin | ||
| Nomifensine is a norepinephrine-dopamine reuptake inhibitor, increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. | ||
| M20404 | Tryptamine | TAAR |
| Tryptamine is a monoamine alkaloid and may play a role as a neuromodulator or neurotransmitter. It is an agonist of hTAAR1. It acts as a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA). Tryptamine is a selective, blood-brain-penetrating 5-HT4 receptor agonist (EC50=1-3 mM) and an endogenous ligand of the aryl hydrocarbon receptor (AHR) (Kd=10-50 nM). Tryptamine promotes intestinal anion secretion and fluid transport by activating G protein-coupled receptors (GPCRs). | ||
| M20793 | Amitriptyline | Serotonin Transporter |
| MK-230; N-750; Ro41575 | ||
| Amitriptyline (MK-230, N-750, Ro41575) is an inhibitor of the serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki values of 3.45 nM and 13.3 nM, respectively, and also inhibits the histamine receptor H1, the histamine receptor H4, 5-HT2, and the Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. It can also inhibit histamine receptor H1, histamine receptor H4, 5-HT2 and Sigma 1 receptor with Ki values of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively, and can be used in studies of depression and neuropathic pain. | ||
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