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Noradrenaline bitartrate monohydrate

Cat. No. M5822
Noradrenaline bitartrate monohydrate Structure


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100mg USD 60  USD60 In stock
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Biological Activity

Noradrenaline bitartrate monohydrate is a direct alpha-adrenergic receptors stimulator.

Chemical Information
Molecular Weight 337.28
Formula C8H11NO3.C4H6O6.H2O
CAS Number 108341-18-0
Solubility (25°C) 64 mg/mL in DMSO
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Zhu JX, et al, Exp Neurol. The role of α₂ adrenoceptor in mediating noradrenaline action in the ventrolateral orbital cortex on allodynia following spared nerve injury.

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Keywords: Noradrenaline bitartrate monohydrate, Levophed supplier, Adrenergic Receptor, inhibitors, activators

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