About 4 results found for searched term "Nilotinib" (0.177 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1912 | Nilotinib | Src-bcr-Abl |
| AMN107 | ||
| Nilotinib (AMN107) is a small molecule Bcr-Abl kinase inhibitor with IC50 less than 30 nM. | ||
| M5330 | Nilotinib (monohydrochloride monohydrate) | Src-bcr-Abl |
| AMN107 | ||
| Nilotinib (AMN-107) is a Bcr-Abl inhibitor with IC50 less than 30 nM. | ||
| M20466 | Nilotinib hydrochloride | Src-bcr-Abl |
| AMN-107 HCl | ||
| Nilotinib hydrochloride is the hydrochloride salt form of nilotinib, an orally bioavailable Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity. | ||
| M4801 | LCL161 | IAP |
| LCL-161 | ||
| LCL161 is an orally bioavailable SMAC mimetic, potently binds to and inhibits multiple IAPs (i.e. XIAP, c-IAP). LCL161 enhanced the proapoptotic effects of nilotinib and PKC412, against leukemic disease in vitro and potentiated the activity of both kinase inhibitors against leukemic disease in vivo. | ||
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