About 15 results found for searched term "Nicotinamide" (0.072 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3314 | Ethionamide | Antibiotic |
| 2-ethylthioisonicotinamide | ||
| Ethionamide(2-ethylthioisonicotinamide) is an antibiotic used in the treatment of tuberculosis. | ||
| M4896 | Nicotinamide | Sirtuin |
| Vitamin B3; Nicotinic acid amide; Niacinamide | ||
| Nicotinamide is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins. Nicotinamide plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. | ||
| M9086 | NAD+ | Enzymes & Coenzymes |
| β-DPN; β-NAD; Coenzyme 1; Nadide；β-Nicotinamide Adenine Dinucleotide | ||
| NAD+, nicotinamide adenine dinucleotide, is a coenzyme that transfers hydrogen ions and is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5'-phosphate via pyrophosphate bonding. NAD+ is the oxidized form of NADH. NAD+ is a coenzyme that is formed by the coupling of ribosylnicotinamide 5'-diphosphate to adenosine 5 '-phosphate coupled by pyrophosphate bonding. | ||
| M9580 | β-Nicotinamide mononucleotide | Sirtuin |
| NMN | ||
| β-nicotinamide mononucleotide (β-NM) is an intermediate in NAD+ biosynthesis produced from nicotinamide (NAM) and phosphoribosyl pyrophosphate (PRPP) by nicotinamide phosphoribosyl transferase enzyme with no toxicity. | ||
| M9681 | JBSNF-000088 (6-Methoxynicotinamide) | Others |
| 6-Methoxynicotinamide | ||
| Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide (NA) analogue, which is a potent NNMT inhibitor. Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide n-methyl transferase (NNMT) inhibitor. The IC50 of monkey NNMT and mouse NNMT were 1.8 µM, 2.8 µM and 5.0 µM, respectively. In animal models of metabolic diseases, JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization and regulates glucose. | ||
| M9697 | Nicotinamide riboside chloride | Sirtuin |
| SRT647; NIAGEN | ||
| Nicotinamide riboside chloride is an orally active NAD+ precursor, increases NAD+ levels and activates SIRT1 and SIRT3. Nicotinamide riboside Chloride is a source of vitamin B3 (niacin) and enhances oxidative metabolism, protection against high fat diet-induced metabolic abnormalities. | ||
| M11201 | Nicotinamide riboside | Sirtuin |
| BETA-nicotinamide ribose;Beta-Nicotinamide Riboside | ||
| Nicotinamide riboside is a precursor to nadir with oral activity that increases NAD levels and activates SIRT1 and SIRT3. Nicotinamide riboside is a source of vitamin B3 (niacin) that enhances oxidative metabolism and prevents metabolic abnormalities induced by a high-fat diet. Nicotinamide riboside can reduce cognitive degradation in transgenic mouse models of Alzheimer's disease. | ||
| M11322 | JBSNF-000088 | Others |
| 6-Methoxynicotinamide | ||
| Jbsnf-000088 (6-methoxynicotinamide) is an analogue of Nicotinamide (NA), and is an effective inhibitor of Nicotinamide n-methyltransferase (NNMT). The IC50 values for human NNMT(hNNMT), Monkey NNMT(mkNNMT) and mouse NNMT(mNNMT) were 1.8 µM, 2.8 µM and 5.0 µM. | ||
| M15978 | 1,4-Dihydro-1-methyl-4-oxonicotinamide | Metabolite/Endogenous Metabolite |
| N-Methyl-4-pyridone-3-carboxamide | ||
| 1,4-Dihydro-1-methyl-4-oxonicotinamide is a metabolite of coffee pyridines, it is a useful organic compound for research related to life sciences. | ||
| M20802 | 6-Aminonicotinamide | Dehydrogenase |
| 6-AN | ||
| 6-Aminonicotinamide is a competitive inhibitor of NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) with Ki of 0.46 μM. 6-Aminonicotinamide (6AN) is an antimetabolite used to inhibit the NADPH-producing pentose phosphate pathway (PPP) in many cellular systems, making them more susceptible to oxidative stress. | ||
| M38904 | Isonicotinamide | Others |
| Isonicotinamide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||
| M45058 | Nikethamide | Others |
| N,N-Diethylnicotinamide | ||
| Nikethamide is a respiratory center activator that can increase the sensitivity of the respiratory center to carbon dioxide by exciting the respiratory center in the medulla oblongata or by stimulating the chemoreceptors in the carotid sinus and the aortic body and reflexively excites the respiratory center, and can be used in studies related to respiratory failure. | ||
| M55383 | N-Methylnicotinamide | Metabolite/Endogenous Metabolite |
| MNA; Nicotinyl Methylamide; N-Methyl-3-pyridinecarboxamide | ||
| N-Methylnicotinamide (MNA, Nicotinyl Methylamide, N-Methyl-3-pyridinecarboxamide) is an active endogenous metabolite that improves endothelial dysfunction and attenuates atherosclerosis by modulating the ADMA-DDAH axis. | ||
| M57364 | 5-Chloronicotinamide | Others |
| 5-Chloronicotinamide | ||
| M58460 | NAD sodium | Metabolite/Endogenous Metabolite |
| β-Nicotinamide adenine dinucleotide sodium salt | ||
| NAD sodium (β-Nicotinamide adenine dinucleotide sodium salt) is an analogue of NAD. NAD sodium can be reduced to β-nicotinamide adenine dinucleotide (NADH) during coupling with reactions which oxidize organic substrates. NAD sodium can be converted to β-nicotinamide adenine dinucleotide (NADH) and passes to the inside of mitochondria that indirectly generates ATP. | ||
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