About 1 result found for searched term "Neferine" (0.178 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4228 | Neferine | NF-κB |
| (-)-Neferine | ||
| Neferine is a bisbenzylisoquinoline alkaloid extracted from Plumbago officinalis, which reduces lipid accumulation and promotes β-oxidation through activation of the AMPK pathway in hepatocytes, and possesses anti-inflammatory, antioxidant, and antipulmonary fibrosis activities. In addition, Neferine potently inhibits NF-κB activation.The affinity Kd value of Neferine for ABCB1 is 0.659 μM.It can be used in studies related to non-alcoholic steatohepatitis (NASH). | ||
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