About 1 result found for searched term "NE 52-QQ57" (0.188 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10634 | NE 52-QQ57 | GPR/FFAR |
| NE52QQ57 | ||
| NE 52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 significantly inhibited the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase 2 (COX2), and prostaglandin E2 (PGE2). | ||
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