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 About 1 result found for searched term "NE 52-QQ57" (0.107 seconds)

Cat.No.  Name Target
M10634 NE 52-QQ57 GPR/FFAR
NE52QQ57
NE 52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 significantly inhibited the AGE-induced increased expression of several key inflammatory cytokines and signaling molecules, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, inducible nitric oxide synthase (iNOS), nitric oxide (NO), cyclooxygenase 2 (COX2), and prostaglandin E2 (PGE2).



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