About 1 result found for searched term "N6F11" (0.125 seconds)
Cat.No. | Name | Target |
---|---|---|
M43932 | N6F11 | Ferroptosis |
2-(chloromethyl)-6-(4-chlorophenyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one | ||
N6F11 is a novel ferroptosis inducer that selectively triggers the ubiquitination degradation of GPX4 by binding to the specific structural domain of TRIM25, a ubiquitinated E3 ligase, which is expressed in tumor cells, leading to ferroptosis in cancer cells. |
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