About 9 results found for searched term "Mangostin" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4355 | α-Mangostin | Others |
| Alpha-mangostin is a dietary xanthone with broad biological activities, such as antioxidant, anti-allergic, antiviral, antibacterial, anti-inflammatory and anticancer effects. It is an inhibitor of mutant IDH1 (IDH1-R132H) with a Ki of 2.85 μM. | ||
| M4356 | β-Mangostin | Antibiotic |
| Beta-mangostin (β -mangostin) is a compound of oxyxanthone present in Cratoxylum arborescens, which has antibacterial and antimalarial activities. The MIC value of beta-mangostin against M. tuberculosis was 6.25 μg/mL. Beta-mangostin showed anti-malarial activity in vitro with IC50 value of 3.00 μg/mL against P. falciparum. Beta-mangostin has strong anticancer activity against various cancers, such as hepatocellular carcinoma and leukemia. | ||
| M4357 | 3-Isomangostin | DNA/RNA Synthesis |
| 3 - Isomangostin from Garciniamangostana. L. Extracted from shell, 3-isomangostin is an effective MutT homolog 1 (MTH1) inhibitor with IC50 value of 52 nM. 3-Isomangostin can be used to develop anticancer agents. | ||
| M17887 | 1-Isomangostin hydrate | Xanthones |
| 1-Isomangostin hydrate | ||
| M17903 | Gamma-Mangostin | COX |
| γ-Mangostin | ||
| Gamma-Mangostin (γ-Mangostin) is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 (COX-2) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin inhibits [3H] spiperone binding to cultured rat aortic myocytes (IC50=3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A (IC50=0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial, antioxidant and anticancer activities. | ||
| M17908 | Isonormangostin | Xanthones |
| Isonormangostin | ||
| M18574 | Dimethylmangostin | Others |
| Dimethylmangostin | ||
| M19271 | Mangostin | Others |
| Mangostin | ||
| M44685 | 1-Isomangostin | Others |
| 1-Isomangostin is an inhibitor of pancreatic lipase. 1-Isomangostin inhibits porcine pancreatic lipase with an IC50 of 34.5 μM. 1-Isomangostin has anti-obesity activity. | ||
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