About 2 results found for searched term "MYCi361" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M20729 | MYCi361 | c-Myc |
| NUCC-0196361 | ||
| MYCi361 is a MYC inhibitor that engages MYC inside cells, disrupts MYC/MAX dimers, and impairs MYC-driven gene expression. MYCi361 binds to MYC with Kd of 3.2 μM. MYCi361 suppresses in vivo tumor growth, increases tumor immune cell infiltration, upregulates PD-L1 on tumors, and sensitizes tumors to anti-PD1 immunotherapy. | ||
| M55742 | N-Demethylansamitocin P-3 | Antibiotic |
| N-Demethylansamitocin P-3 can be prepared from Ansamitocin (an antitumor ansamycin antibiotic) by Streptomyces minutiscleroticus IFO 13361. | ||
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