About 2 results found for searched term "MTX-23" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M57286 | MTX-23 | PROTAC |
| PROTAC AR-V7 degrader-2; MTX23 | ||
| MTX-23 is an AR-based PROTAC. MTX-23 inhibits CaP cellular proliferation by degrading AR-V7 and AR-FL. MTX-23 induces apoptosis. | ||
| M55660 | MTX-531 | EGFR/HER2 |
| MTX531 | ||
| MTX-531 is a first-in-class, potent and selective inhibitor of EGFR and PI3K, with IC50s of 14.7 nM and 1.1-233 nM (differ in subtype). MTX-531 can also act as a weak agonist of PPARγ, with the EC50 of 3.4 μM in 293H cells. | ||
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