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 About 5 results found for searched term "MMAF" (0.057 seconds)

Cat.No.  Name Target
M5041 MMAF Microtubule
Monomethylauristatin F
Monomethylauristatin F(MMAF) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than MMAE; antibody compound cytotoxin.*The compound is unstable in solutions, freshly prepared is recommended
M10397 McMMAF Drug-Linker Conjugates for ADC
Maleimidocaproyl monomethylauristatin F
McMMAF is a protective group-conjugated MMAF. *The compound is unstable in solutions, freshly prepared is recommended
M10403 MC-Val-Cit-PAB-MMAF Drug-Linker Conjugates for ADC
MC-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC with antitumor activity by using the tubulin inhibitor, MMAF, linked via cathepsin cleavable MC-Val-Cit-PAB.
M13452 MMAF-OMe Others
Monomethyl auristatin F methyl ester
MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively.
M13692 MMAF hydrochloride Microtubule
Monomethylauristatin F hydrochloride
MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent.



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