About 5 results found for searched term "MM-102" (0.152 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2861 | MM-102 | Histone Methyltransferase |
| HMTase Inhibitor IX | ||
| MM-102 is a high-affinity peptidomimetic MLL1 inhibitor with IC50 of 0.4 μM. | ||
| M13848 | MM-102 TFA | Histone Methyltransferase |
| HMTase Inhibitor IX TFA | ||
| MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide. | ||
| M9692 | IAXO-102 | TLR |
| Iaxo-102 is an antagonist of TLR4 and inhibits the TLR4 signaling pathway. Iaxo-102 inhibits phosphorylation of MAPK and P65 NF-KB and expression of TLR4 and TLR4-dependent inflammatory proteins. Iaxo-102 inhibits the development of experimental abdominal aortic aneurysms. | ||
| M22501 | SM-102 | Liposome |
| SM102 | ||
| ALC-0159 is a lipid conjugate of polyethylene glycol that can be used as an immunosuppressant SM-102 is an ionizable aminolipid with a terminal hydroxyl group in the head group, which reduces the hydration of the head group and improves hydrogen bonding interactions with nucleic acids, thus enhancing transfection.SM-102 can be used for the preparation of lipid nanoparticles (LNPs), as well as for the lipid nanoparticle delivery of | ||
| M54581 | NIC-0102 | Proteasome |
| NIC-0102 is an orally potent proteasome inhibitor (pIC50=7.55) that specifically inhibits NLRP3 inflammasome activation.NIC-0102 showed potent anti-inflammatory effects in vivo in a DSS-induced ulcerative colitis model. In addition, NIC-0102 inhibited the production of pro-IL-1β. | ||
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