MM-102 - Search Results | AbMole BioScience

About 5 results found for searched term "MM-102" (0.117 seconds)

Cat.No.	Name	Target
M2861	MM-102	Histone Methyltransferase
	HMTase Inhibitor IX
	MM-102 is a high-affinity peptidomimetic MLL1 inhibitor with IC50 of 0.4 μM.
M13848	MM-102 TFA	Histone Methyltransferase
	HMTase Inhibitor IX TFA
	MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is >200 times more potent than the ARA peptide.
M9692	IAXO-102	TLR
	Iaxo-102 is an antagonist of TLR4 and inhibits the TLR4 signaling pathway. Iaxo-102 inhibits phosphorylation of MAPK and P65 NF-KB and expression of TLR4 and TLR4-dependent inflammatory proteins. Iaxo-102 inhibits the development of experimental abdominal aortic aneurysms.
M22501	SM-102	Liposome
	SM102
	ALC-0159 is a lipid conjugate of polyethylene glycol that can be used as an immunosuppressant SM-102 is an ionizable aminolipid with a terminal hydroxyl group in the head group, which reduces the hydration of the head group and improves hydrogen bonding interactions with nucleic acids, thus enhancing transfection.SM-102 can be used for the preparation of lipid nanoparticles (LNPs), as well as for the lipid nanoparticle delivery of
M54581	NIC-0102	Proteasome
	NIC-0102 is an orally potent proteasome inhibitor (pIC50=7.55) that specifically inhibits NLRP3 inflammasome activation.NIC-0102 showed potent anti-inflammatory effects in vivo in a DSS-induced ulcerative colitis model. In addition, NIC-0102 inhibited the production of pro-IL-1β.