About 2 results found for searched term "MI-2-2 " (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28489 | MI-2-2 | Epigenetic Reader Domain |
| MI-2-2 is a potent menin-MLL inhibitor. MI-2-2 binds to menin with low nanomolar affinity (Kd=22nM) and very effectively disrupts the bivalent protein-protein interaction between menin and MLL. MI-2-2 has specific and very pronounced activity in MLL leukemia cells, including inhibition of cell proliferation, down-regulation of Hoxa9 expression, and differentiation. | ||
| M57095 | Thalidomide-O-amido-PEG4-C2-NH2 | E3 Ligase Ligand-Linker Conjugates |
| Thalidomide-O-amido-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. | ||
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